Human Follicular Fluid, Clinical Use of Proteomics Analysis in Identification of Infertility

Abstract: Introduction: In present situation infertility is one of the chief problem for reproductive couples due to multiple factors including lifestyle. Infertility thought be caused by both male and female in 27 percent cases, with 15 cases being idiopathic. Assisted technologies are used these overcome problems related infertility, but success rate ART appreciated WHO if it reaches 30%. About 70% non-successful fact that molecular mechanism human system poorly understood. Materials Methods: A systematic review was carried out using which pubmed, sciencedirect, scifinder, google scholar databases. We followed standard criterion inclusion exclusion recommended Cochrane system. Information collected from selected articles were compared summarized tables Figures. Results: Proteomics a promising approach identifying possible biomarkers treatment management. The use OMICS technology develop diagnostic therapeutic techniques increase efficacy critical. Tandem mass spectrometry (LCMS/ MS) identify peptides proteins. Using advance proteomics tools such as SELDI-TOF, MALDI-TOF stressing importance protein pregnancy maintenance fertilization. Conclusion: conclude this study analysis can help potential field infertility. Further serious extensive research very much required research. Keywords: Infertility, technologies, Proteomics, Therapeutic Management.